Okay, let's admit that being a very powerful indie-rock composition, Radioactive is not something to be playing modestly on your piano. This a piece demanding entourage, a mix of percussion and bass instruments to make it reach its biggest effect. However, the melody line is so universal that the piece can sound catchy and contagious on any instrument whatsoever. I do like the vocal versions, too.
They play this hit so virtuously live at concerts!